當前位置： 2022-2023學年北京五十五中高二（下）月考英語試卷（3月份）> 試題詳情

A group of researchers led by Patrick Yu-Wai-Man.an ophthalmologist （眼科醫(yī)師） at Cambridge University，investigated a new genetic therapy for a form of blindness.Officially，their study was a failure.But it was also a great success，for 29 of the 37 participants reported big improvements in their vision.
   The disease in question is Leber Hereditary Optic Neuropathy （LHON）（遺傳性視神經(jīng)病變） .A defective gene leads to sudden and rapid loss of sight，with many sufferers becoming legally blind within a year.It affects between one in 30，000 and one in 50，000 people.Men in their 20s and 30s are particularly at high risk.Since most cases are caused by a mutation （突變） in a single gene，LHON is a good candidate for gene therapy，a form of genetic engineering which aims to replace the defective gene with a working one.
   With that in mind.Dr Yu-Wai-Man and his colleagues loaded up a changed virus with a corrected copy of the gene and injected it into their patients' eyes.The researchers controlled the experiment by injecting only one of each patient's eyes--chosen at random--with the virus.The other eye was given a fake injection.Using two eyes in the same patient makes for a perfect control.
   The surprise came several months later.The researchers had hoped to see a big improvement in the treated eyes，compared with the untreated ones.They did not，for which the study failed in its primary objective.Instead，in more than three quarters of their patients，they saw significant improvements in both eyes.
   On the face of it，that was odd.Only one eye had received the treatment，after all.Follow-up studies in monkeys confirmed what the researchers had suspected.The virus，it seemed，had found a way to travel from one eye to the other，probably via the optic nerve.Tissues and fluids samples from monkeys given the same treatment as the human patients showed viral DNA in both eyes，not just one.
   Although it had a happy outcome in this case，the prospect of a gene-therapy virus travelling to places it is not intended to go to might worry regulators.Fortunately，the researchers found no trace of the virus elsewhere in the monkeys' bodies.And.though the study was technically a failure，its practical success means that an effective treatment for LHON may at last be in reach.

（1）LHON is chosen in this study because it
D
D

A．can be easily cured
B．a(chǎn)ffects young males mostly
C．is a common disease among people
D．results from a mutation in a single gene
（2）Why was the study a great success despite a failure officially？
B
B

A．Some participants suffered loss of sight
B．The vision of both eyes improved greatly
C．All the participants gave positive feedback
D．The virus didn't replace the damaged gene
（3）The experiment on monkeys is mentioned in order to
A
A

A．confirm the virus travels across eyes
B．prove the virus can affect other body parts
C．show the effect of the treatment on animals
D．highlight regulators' worry about gene-therapy
（4）Which is the best title for the passage？
C
C

A．The Future of Gene Therapy
B．The Blessing for Eye Patients
C．Gene Therapy：Eyeball to Eyeball
D．Virus Treatment：From Humans to Monkeys

【考點】健康；說明文．

【答案】D；B；A；C

【解答】

【點評】

聲明：本試題解析著作權屬菁優(yōu)網(wǎng)所有，未經(jīng)書面同意，不得復制發(fā)布。

當前模式為游客模式，立即登錄查看試卷全部內(nèi)容及下載

發(fā)布：2024/7/11 8:0:9組卷：1引用：1難度：0.5

相似題

1．A Many people miss out on learning opportunities because they let their feelings get in the way.They refuse （1）

（learn） or ignore what is said because of who the speaker is.It is true that we cannot help （2）

（dislike） some people.But do not forget you can still learn from them.Active learners do not judge people （3）

（base） on first impressions or personal feelings.Instead，they separate the message from the messenger.
B A person with a photographic memory could remember every detail of a picture，a book or an event many years later，but it has not been proved （4）

there are people who really have photographic memories.Yet，there are some people who do have （5）

（amaze） memories.For example，Daniel Tammet can remember the first 22，514 digits of pi （π） and Stephen Wiltshire can draw a detailed picture of a city from memory after flying over it in a helicopter.They are both good （6）

remembering particular things for a limited time.
C Most gardeners will probably say gardening （7）

（be） good for you.According to a study，people who garden have a （8）

（healthy） diet，get more exercise，and feel less stress.Researchers studied the benefits of gardening in shared community gardens （9）

people work together.They suggest gardening may reduce stress because it exposes people to nature，while community gardens also provide （10）

（chance） for social interaction.Therefore，they hope the results will encourage doctors and government leaders to regard community gardens as a vital part of the public health system.
發(fā)布：2024/9/6 7:0:8組卷：12引用：1難度：0.5
解析
2．Smiling is a great way to make yourself stand out while helping your body to function better.It is just one fun way to live longer，read about the others and try as many as you can，（1）

   Smiling Makes Us Attractive
   （2）

   There is an attraction factor.We want to know a smiling person and figure out what is so good.Frowns and sorrows all push people away-but a smile draws them in.When someone is smiling they lighten up the room，change the moods of others，and make things happier.Smile a lot and you will draw people to you.
   （3）

   Stress can really show up in our faces，while smiling helps to prevent us from looking tired，worn down，and overwhelmed.When you are stressed，it is of great significance to take time to put on a smile，which can trick the body into helping you change your mood.The stress should be reduced and you'll be better able to take action.
   Smiling Lowers Your Blood Pressure
   When you smile，there is a measurable reduction in your blood pressure.（4）

Sit for a few minutes；take a reading.Then smile for a minute and take another reading while still smiling.Do you notice a difference？
   Smiling Makes You Seem Successful
   Smiling people appear more confident，are more likely to be promoted，and more likely to be approached.（5）

Next time you are feeling down，try putting on a smile.There's a good chance your mood will change for the better.

A.Smiling Relieves Stress
B.We are drawn to people who smile.
C.Here are some reasons to keep smiling in your daily life.
D.Give it a try if you have a blood pressure monitor at home.
E.The muscles we use to smile lift the face，making a person appear younger.
F.When we smile our body is sending the rest of us a message that "Life is Good !"
G.Put on a smile at meetings and appointments and people will react to you differently.
發(fā)布：2024/10/19 14:0:1組卷：10引用：2難度：0.4
解析
3．Many people believe that there is some truth in the saying Laughter is the best medicine．（1）

Laughter helps relieve pain，strengthen the immune system and reduce stress．Laughter stimulates（激發(fā)） hormones which make us feel happy．Laughter also increases the flow of blood throughout the body and has benefits which are similar to the ones you get by doing exercise．
   （2）

Children exposed to funny films and cartoons before major medical procedures are able to cope better with pain and anxiety．（3）

These are professional clowns who are sent to hospitals and wards to entertain and distract sick children．
   Laughter therapy has become very popular in recent years and as a result，more and more laughter clubs are starting to open up in cities and towns all over the world．At a laughter session，a trained therapist instructs the group to perform a series of exercises which are designed to produce laughter．（4）

And it takes them some time to get rid of their inhibitions（心理抑制）．They might even start off with fake laughter，but this doesn't matter because our bodies can't tell the difference，and the results are the same．Moreover，laughter is contagious（傳染的）．（5）

   So next time you feel ill，stressed out or depressed，try watching a funny film or try remembering an amusing incident in your life．You will soon feel better．

A．If one person starts giggling，it is unavoidable that everyone else will be drawn in．
B．Laughter helps you focus．
C．This finding has led to so-called clown doctors．
D．In fact，research done by scientists has shown that laughter has a lot of health benefits．
E．Laughter makes the world a better and more colorful place．
F．Some people may find the idea embarrassing at first．
G．Using laughter therapy in children's hospitals has proven to be invaluable．
發(fā)布：2024/10/21 14:0:2組卷：12引用：2難度：0.5
解析

把好題分享給你的好友吧~~